BPC-157

BPC-157, formally known as Body Protection Compound-157, is a stable pentadecapeptide with the amino acid sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV). It has a molecular weight of approximately 1419.53 Da and carries a net negative charge at physiological pH. The peptide is a partial sequence derived from a larger protective protein identified in human gastric juice, designated BPC. Unlike many peptides, BPC-157 is notably stable in human gastric juice for extended periods (over 24 hours), an unusual property for a peptide of its size that makes it of interest for both injectable and oral research protocols.

For research applications, BPC-157 is typically stored as a lyophilized powder at -20C, where it remains stable for extended periods. Once reconstituted in bacteriostatic water (0.9% benzyl alcohol), the solution is refrigerated at 2-8C. Repeated freeze-thaw cycles degrade the peptide and are avoided. Reconstitution is performed by gently directing bacteriostatic water down the vial wall rather than directly onto the powder cake to limit foaming.